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Author(s): Ishank Jhanji1

Email(s): 1ishank714@modernschool.net


    Modern school, Barakhamba Road, New Delhi 110001, India

Published In:   Volume - 3,      Issue - 2,     Year - 2023

DOI: 10.55878/SES2022-3-2-4  

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Revived demand in microbial acetone-butanol-ethanol (ABE) fermentation has encouraging researchers for technological advancement in this field to produce sustainable and environmental being biofuels. The microbial species of genera Clostridia are commonly used for production of ABE. ABE fermentation in Clostridiais biphasic with an initial acidogenic phase followed by solvent ogenic phase, where the assimilated acids are used to produce ABE. The obtained mixture from ABE fermentation has a capacity to seamlessly blend with gasoline. However, inherent problems associated with ABE fermentation are significant substrate cost, solvent toxicity, relatively inadequate product concentration, and substantial purification cost. ABE mixture as a drop-in fuel is widely studied by researchers but rarely reviewed to understand its techno economical analysis and inherent challenges, so far. Therefore, the present work summarizes the recent advancement in ABE fermentation in terms of upstream and downstream processes along with its inherent challenges to achieve high yield and productivity. The present review will be facilitative opportunity to consider ABE mixture as a drop-in biofuel in upcoming days.

Cite this article:
Ishank Jhanji (2023), Cutting-edge breakthroughs in the acetone-butanol-ethanol fermentation technology, Spectrum of Emerging Sciences, 3 (2) 2023, 21-27, 10.55878/SES2022-3-2-4DOI: https://doi.org/10.55878/SES2022-3-2-4

[1] Mahalingam L, Abdulla R, Sani SA, Sabullah MK, Faik AM, Misson M.  Lignocellulosic Biomass – A Sustainable Feedstock for Acetone-Butanol-Ethanol Fermentation. Periodica Polytechnica Chemical Engineering 2022; 66(2), 279–296. https://doi.org/10.3311/ppch.18574

[2] Borah AJ, Roy K, Goyal A, Moholkar VS. Mechanistic Investigations in Biobutanol Synthesis via Ultrasound–Assisted ABE Fermentation Using Mixed Feedstock of Invasive Weeds. Bioresource Technol 2018. doi: https://doi.org/10.1016/j

[3] Gottumukkala LD, Mathew AK, Abraham A, Sukumaran R. Biobutanol production: microbes, feedstock, and strategies. In Elsevier eBooks 2019; 355–377. https://doi.org/10.1016/b978-0-12-816856-1.00015-4

[4] Kumar M, Goyal Y, Sarkar A, Gayen K. Comparative economic assessment of ABE fermentation based on cellulosic and non-cellulosic feedstocks. Applied Energy 2012; 93, 193–204. https://doi.org/10.1016/j.apenergy.2011.12.079

[5]  Nalawade K, Kadam V, Behera S, Konde K, Patil S. Sustainable butanol biofuels. Chapter 6 Mechanisms and Applications of Biofuel. In CRC Press eBooks 2023. https://doi.org/10.1201/9781003165408

[6] Li Y, Wei T, Chen Y, Liu J, Lee CFF. Potential of acetone-butanol-ethanol (ABE) as a biofuel. Fuel 2019;  242, 673–686. https://doi.org/10.1016/j.fuel.2019.01.063

[7] Tsai TY, Lo YC, Dong C, Nagarajan D, Chang JS, Lee DH. Biobutanol production from lignocellulosic biomass using immobilized Clostridium acetobutylicum. Applied Energy 2020; 277, 115531. https://doi.org/10.1016/j.apenergy.2020.115531

[8] Qureshi N, Blaschek HP. Recent advances in ABE fermentation: hyper-butanol producing Clostridium beijerinckii BA101. Journal of Industrial Microbiology & Biotechnology 2001; 27, 287 – 291.

[9] Li S, Huang L, Ke C, Pang Z, Liu L. Pathway dissection, regulation, engineering and application: lessons learned from biobutanol production by solventogenic clostridia. Biotechnology for Biofuels 2020; 13(1). https://doi.org/10.1186/s13068-020-01674-3.

[10] Schwarz K, Grosse-Honebrink A, Derecka K, Rotta C, Zhang Y, Minton NP. Towards improved butanol production through targeted genetic modification of Clostridium pasteurianum. Metabolic Engineering 2017; 40, 124–137. https://doi.org/10.1016/j.ymben.2017.01.009.

[11] Du G, Che J, Wu Y, Wang Z, Jiang Z, Feng J, Xue C. Disruption of hydrogenase gene for enhancing butanol selectivity and production in Clostridium acetobutylicum. Biochemical Engineering Journal 2021; 171, 108014. https://doi.org/10.1016/j.bej.2021.108014

[12] Wen Z, Li Q, Liu J, Jin M, Yang S. Consolidated bioprocessing for butanol production of cellulolytic Clostridia: development and optimization. Microbial Biotechnology 2019; 13(2), 410–422. https://doi.org/10.1111/1751-7915.13478

[13] Jang Y, Lee JY, Lee J, Park JH, Im JA, Eom M, Lee JH, Lee SH, Song H, Cho JH, Seung DY, Lee SY. Enhanced butanol production obtained by reinforcing the direct butanol-forming route in Clostridium acetobutylicum. MBio 2012; https://doi.org/10.1128/mbio.00314-12

[14] Jiang Y, Xu C, Dong F, Yang Y, Jiang W, Yang S.  Disruption of the acetoacetate decarboxylase gene in solvent-producing Clostridium acetobutylicum increases the butanol ratio. Metabolic Engineering 2009; 11(4–5), 284–291. https://doi.org/10.1016/j.ymben.2009.06.002

[15] Mann MS, Lütke‐Eversloh T. Thiolase engineering for enhanced butanol production inClostridiumacetobutylicum. Biotechnology and Bioengineering 2012; 110(3), 887–897. https://doi.org/10.1002/bit.24758

[16] Qureshi N, Saha BC, Hector RE, Cotta MA. Removal of fermentation inhibitors from alkaline peroxide pretreated and enzymatically hydrolyzed wheat straw: Production of butanol from hydrolysate using Clostridium beijerinckii in batch reactors. Biomass and Bioenergy 2008a; 32(12), 1353–1358. https://doi.org/10.1016/j.biombioe.2008.04.009

[17] Qureshi N, Ezeji TC, Ebener J, Dien BS, Cotta MA. Blaschek HP. Butanol production by Clostridium beijerinckii. Part I: use of acid and enzyme hydrolyzed corn fiber. Bioresoure Technology 2008b; 99:5915–22.

[18] Qureshi N, Saha BC, Dien B, Hector RE, Cotta MA. Production of butanol (a biofuel) from agriculture residues: Part I- Use of barley straw hydrolysate. Biomass and Bioenergy 2010a; 34(4), pp. 559–565.

[19] Qureshi N, Saha BC, Hector RE, Dien B, Hughes S, Liu S, Iten L, Bowman MJ, Sarath G, Cotta MA. Production of butanol (a biofuel) from agricultural residues: Part II- Use of corn stover and switchgrass hydrolysate. Biomass and Bioenergy 2010b;  34(4), pp. 566–571.

[20] Paniagua-García AI, Hijosa‐Valsero M, Díez-Antolínez R, Sánchez M, Coca M. Enzymatic hydrolysis and detoxification of lignocellulosic biomass are not always necessary for ABE fermentation: The case of Panicum virgatum. Biomass and Bioenergy 2018; 116, 131–139. https://doi.org/10.1016/j.biombioe.2018.06.006

[21] Su C, Li Q, Cai D, Chen B, Chen H, Zhang C, Si Z, Wang Z, Li G, Qin P. Integrated ethanol fermentation and acetone-butanol-ethanol fermentation using sweet sorghum bagasse. Renewable Energy 2020; 162, 1125–1131. https://doi.org/10.1016/j.renene.2020.07.119

[22] Kaushal M, Ahlawat S, Makut BB, Goswami G, Das D. Dual substrate fermentation strategy utilizing rice straw hydrolysate and crude glycerol for liquid biofuel production by Clostridium sporogenes NCIM 2918. Biomass and Bioenergy 2019; 127, 105257, .https://doi.org/10.1016/j.biombioe.2019.105257.

[23] Zhang X, Feng X, Zhang H, Wei Y. Utilization of steam-exploded corn straw to produce biofuel butanol via fermentation with a newly selected strain of Clostridium acetobutylicum. BioResources 2018; 13(3), 5805–5817.

[24] Ezeji TC, Qureshi N, Blaschek HP. Continuous butanol fermentation and feed strach retrogradation: butanol fermentation sustainability using Clostridium beijerinckii BA101. Journal of Biotechnology 2005; 115(2), 179–187. https://doi.org/10.1016/j.jbiotec.2004.08.010.

[25] Fathima AA, Sanitha M, Kumar T, Iyappan S, Ramya M. Direct utilization of waste water algal biomass for ethanol production by cellulolytic Clostridium phytofermentas DSM1138. Bioresource Technology 2015; 202, pp. 253–256, https://doi.org/10.1016/j.biortech.2015.11.075

[26] Gao K, Orr V, Rehmann L. Butanol fermentation from microalgae-derived carbohydrates after ionic liquid extraction. Bioresource Technology 2016; 206, pp. 77–85, .https://doi.org/10.1016/j.biortech.2016.01.036

[27] Efremenko E, Nikolskaya A, Lyagin I, Senko O, Makhlis T, Stepanov N. Production of biofuels from pretreated microalgae biomass by anaerobic fermentation with immobilized Clostridium acetobutylicum cells. Bioresour technol 2012; 114:342–8.

[28] Chang Z, Cai D, Wang Y, Chen C, Fu C, Wang G, Qin P, Wang Z, Tan T. Effective multiple stages continuous acetone–butanol–ethanol fermentation by immobilized bioreactors: Making full use of fresh corn stalk. Bioresource Technology 2016; 205, 82–89. https://doi.org/10.1016/j.biortech.2016.01.034

[29] González-Peñas H, Lú-Chau TA, Moreira MT, Lema JM. Solvent screening methodology for in situ ABE extractive fermentation. Applied Microbiology and Biotechnology 2014; 98(13), 5915–5924. https://doi.org/10.1007/s00253-014-5634-6

[30] Haigh KF, Petersen AM, Gottumukkala LD, Mandegari M, Naleli K, Görgens JF. Simulation and comparison of processes for biobutanol production from lignocellulose via ABE fermentation. Biofuels. Bioproducts and Biorefining 2018; 12(6), 1023–1036. https://doi.org/10.1002/bbb.1917





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